Autoimmune conditions, a group of diseases where the body's immune system mistakenly attacks its own tissues, have long puzzled medical researchers and clinicians alike. In our office, we use laboratory testing including antibody markers, and a customized panel to find the root cause of health conditions. In this article, you will learn some of the common root causes of autoimmune issues and some methods we use to help these individuals, along with one of our clients ’ stories of her road to recovery. You can find her testimony here.
Kristen Lab Results Before and After Care
Genetic Predisposition:
A strong genetic component underlies many autoimmune disorders. Individuals with a family history of autoimmune diseases are at a higher risk of developing similar conditions. Specific genes, such as those encoding for certain human leukocyte antigen (HLA) molecules, play a crucial role in regulating immune responses. However, genetic predisposition alone does not fully account for the onset of autoimmune conditions, suggesting that environmental factors also contribute significantly.
Environmental Triggers:
Environmental factors, ranging from infections to dietary components, can trigger or exacerbate autoimmune responses in genetically susceptible individuals. Chronic infections, such as viral or bacterial pathogens, can disrupt immune tolerance and trigger an autoimmune cascade. Environmental pollutants, toxins, and dietary antigens may also activate the immune system, leading to aberrant immune responses against self-antigens.
Leaky Gut and Dysbiosis:
The gut microbiome, consisting of trillions of microorganisms, plays a crucial role in immune regulation and tolerance. Disruption of the gut barrier, commonly referred to as "leaky gut," allows harmful substances to enter the bloodstream, triggering immune reactions. Dysbiosis, an imbalance in the gut microbiota composition, has also been implicated in the pathogenesis of autoimmune diseases. Alterations in gut microbial diversity and function can lead to immune dysregulation and promote autoimmunity.
Hormonal Influences:
Hormonal fluctuations, particularly in estrogen and testosterone levels, have been associated with the prevalence and severity of autoimmune diseases. Women are disproportionately affected by many autoimmune conditions, suggesting a potential role for sex hormones in modulating immune responses. Estrogen, in particular, has been shown to enhance immune activation, while testosterone may exert immunosuppressive effects. The intricate interplay between sex hormones and the immune system underscores the complexity of autoimmune pathogenesis.
Chronic Inflammation:
Chronic inflammation is a hallmark feature of autoimmune diseases, perpetuating tissue damage and disease progression. Dysregulated immune responses lead to the production of pro-inflammatory cytokines, chemokines, and autoantibodies, contributing to tissue destruction and organ dysfunction. Persistent inflammation can further disrupt immune tolerance mechanisms, exacerbating autoimmune pathology.
Psychological Stress:
Psychological stressors, such as chronic stress or trauma, have emerged as significant contributors to autoimmune dysregulation. The intricate bidirectional communication between the brain and the immune system, known as psychoneuroimmunology, influences immune function and susceptibility to autoimmune diseases. Stress-induced alterations in hormonal balance, neurotransmitter signaling, and immune cell activity can exacerbate inflammatory responses and trigger autoimmune flares.
In conclusion, autoimmune diseases represent a complex interplay between genetic predisposition, environmental triggers, hormonal influences, chronic inflammation, gut dysbiosis, and psychological stress.
If you are struggling with an autoimmune condition, even if you have not been diagnosed, it is important to have laboratory testing to understand your root cause.
Together, we can start on your journey to reclaiming your health, much like our client Kristen! Find her powerful testimony here.
This information should not be substituted for medical or chiropractic advice. Any and all healthcare concerns, decisions, and actions must be done through the advice and counsel of a healthcare professional who is familiar with your updated medical history.
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